Cohesion is established during DNA replication utilising chromosome associated cohesin rings as well as those loaded de novo onto nascent DNAs

ABSTRACT: Cohesin is established by two parallel pathways during DNA replication. Chromosome associated cohesin is converted to cohesive structures and this depends on four protein associated with the replisome; Tof1/Csm3, Ctf4 and Chl1 (TCCC). In TCCC mutants, chromosome associated cohesin is evicted from the DNA during S phase.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE151551 | GEO | 2020/06/16

REPOSITORIES: GEO