Transcriptomics of Human Liver Ischemia and Reperfusion Injury

ABSTRACT: For orthotopic liver transplants, ischemia-reperfusion injury (IRI) is known to compromise allograft survival. To better understand the transcriptomics of immune responses underlying liver transplant IRI, RNA-seq was performed on liver biopsies from 23 IRI+ and 17 IRI- patients, both pre-transplant and post-transplant. Genes that are differentially expressed in IRI+ samples, along with the pathways enriched for by those genes, were identified.

ORGANISM(S): Homo sapiens

PROVIDER: GSE151648 | GEO | 2020/08/07

REPOSITORIES: GEO