Transcriptional response of mce3R induction and ctpD disruption in Mycobacterium tuberculosis CDC1551

ABSTRACT: We identified mce3R and ctpD as genes that could alter M tuberculosis (Mtb) response to isoniazid when perturbed using a regulatory network-based TRIP screen [see associated data at PRJNA483505]. To investigate the mechanisms underlying this response, we performed RNAseq on genetically perturbed mutant strains either in the presence or absence of isoniazid.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE151991 | GEO | 2020/08/11

REPOSITORIES: GEO