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Potential modulation of Puf3 chromatin association mediated by Rpb4

ABSTRACT: Gene expression involving RNA polymerase II is regulated by the concerted interplay between mRNA synthesis and degradation, a crosstalk where mRNA decay machinery impacts transcription and transcription machinery influences mRNA stability. Rpb4, and likely the dimer Rpb4/7 seem to be the central components of the RNA pol II governing these processes. Here we investigate the effect of ∆rrp4 on the potential chromatin association of the RNA binding protein Puf3 to chromatin in S. cerevisiae.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE152093 | GEO | 2022/11/09

REPOSITORIES: GEO

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