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Multiplexed functional assessment of dominant genetic variants in CARD11

ABSTRACT: We describe the use of saturation genome editing to measure the effects of CARD11 variants on protein function, splicing and lymphoma cell survival. We find the results to predict the clinical effects of the variants.

ORGANISM(S): Homo sapiens

PROVIDER: GSE152129 | GEO | 2020/07/01

REPOSITORIES: GEO

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