Transcriptomics

Dataset Information

31

Transcriptome analysis of in vitro endotoxin tolerant human monocytes


ABSTRACT: Monocyte exposure to lipopolysaccharide (LPS) induces a transient state in which these cells are refractory to further endotoxin stimulation. Here we demonstrate the transcriptome analysis of in vitro generated LPS refractory monocytes upon subsequent re-exposure to LPS for different time points. Overall design: Total RNA obtained from human monocyte exposure treated with LPS for 3h, 6h, or 24h, subsequent to endotoxin tolerization or not.

INSTRUMENT(S): Illumina humanRef-8 v2.0 expression beadchip

ORGANISM(S): Homo sapiens  

SUBMITTER: Eduardo Lopez-Collazo  

PROVIDER: GSE15219 | GEO | 2009-03-14

SECONDARY ACCESSION(S): PRJNA116467

REPOSITORIES: GEO

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