Functional genomic analyses of iPSC-derived pancreatic progenitor cells

ABSTRACT: The goal of this study is to molecularly characterize regulatory variation in pancreatic progenitor cells (PPC). Here, we derived PPC from iPSCs of nine iPSCORE individuals (DeBoever et al., 2017; Panopoulos et al., 2017), and generated RNA-seq, ATAC-seq, scRNA-seq, and snATAC-seq. We strive to understand the role of functional genetic variation during fetal pancreatic development that later give rise to adult pancreatic diseases.

ORGANISM(S): Homo sapiens

PROVIDER: GSE152610 | GEO | 2022/12/02

REPOSITORIES: GEO