Morphological and genomic shifts in mole-rat queens increase fecundity but reduce skeletal integrity

ABSTRACT: We sequenced polyA-selected RNA from bone marrow derived cells from 47 bone samples collected from 16 captive, adult female Damaraland mole-rats (Fukomys damarensis). The 16 females were experimentally manipulated to either remain as nonbreeders (either as helpers or solitaires) or become breeders, and breeding status was maintained for over 1 year prior to tissue collection and cell culture. A subset of cultured cells were treated for 24 hours with 10 nM estradiol prior to sample collection.

ORGANISM(S): Fukomys damarensis

PROVIDER: GSE152659 | GEO | 2021/04/28

REPOSITORIES: GEO