EATP-responsive synthetic yeast ameliorate TNBS-induced colitis

ABSTRACT: By combining directed evolution and synthetic biology, we engineered novel synthetic yeasts probiotics for the dynamic modulation of intestinal inflammation. In this experiment we treated TNBS-colitis induced mice with these probiotics and test the amelioration of immune response in the transcriptional level in the colon.

ORGANISM(S): Mus musculus

PROVIDER: GSE152869 | GEO | 2021/04/22

REPOSITORIES: GEO