Targeted single cell RNA sequencing of T cells infiltrated in mouse gastric cancer.

ABSTRACT: YTN2 and YTN16 cells are chemically induced gastric cancer cell lines. YTN2 is spontaneously regressed in C57BL/6 mice in CD8+ T cell-dependent manner, while YTN16 grows progressively. To investigate tumor infiltrating T cells, we performed single-cell RNA-Seq of CD4+ and CD8+ T cells in YTN2 and YTN16 gastric tumor-bearing mice for 44 T cell-related genes (Supplementary Table 1).

ORGANISM(S): Mus musculus

PROVIDER: GSE152888 | GEO | 2020/10/28

REPOSITORIES: GEO