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Methylation and gene expression data obtained from Dnmt3b+/- peripheral T-cell lymphomas.

ABSTRACT: Dnmt3b is a tumor suppressor in oncogene-driven lymphoid and myeloid malignancies in mice. However, it is poorly understood whether reduced Dnmt3b activities can initiate malignant hematopoiesis. We modulated Dnmt3b activity in vivo by generating Dnmt3b+/− mice expressing one wild-type allele. Here, we analyzed methylation and gene expression in Dnmt3b+/- peripheral T-cell lymphomas (PTCLs).

ORGANISM(S): Mus musculus

PROVIDER: GSE154270 | GEO | 2020/12/31

REPOSITORIES: GEO

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