Cpxm2 as a novel candidate for cardiac hypertrophy and failure in hypertension [Illumina]

ABSTRACT: To identify novel targets in left ventricular (LV) hypertrophy (LVH) we initiated comparative transcriptome analysis between genetic models derived from stroke-prone spontaneously hypertensive rats (SHRSP) and Fischer (F344). Previous genetic studies in the SHRSP/F344 model confirmed the presence of a major quantitative trait locus (QTL) for LV mass on rat chromosome (RNO) 1. We assigned carboxypeptidase X 2 (Cpxm2) to a genetic locus for LV mass identified in SHRSP. We assigned carboxypeptidase X 2 (Cpxm2) to a genetic locus for left ventricular mass.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE154326 | GEO | 2023/07/10

REPOSITORIES: GEO