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Chromatin accessibility in human K562 erythroleukemia cells profiled upon heat shock, recovery, and heat-induced transcriptional memory

ABSTRACT: ATAC-seq in human K562 erythroleukemia cells that were either unconditioned (s_uC and HSS_uC), preconditioned with a single heat shock exposure (s_pC), or preconditioned with multiple heat exposures (HSS_pC). After two day recovery from the preconditioning, during which the cells underwent two mitotic divisions, the cells were additionally subjected to a single heat shock to analyze heat-induced changes in chromatin accessibility in unconditioned versus preconditioned cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE154744 | GEO | 2021/04/01

REPOSITORIES: GEO

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Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells.

Project description:Precision run-on sequencing (PRO-seq) of nascent RNA synthesis across the human genome. The PRO-seq data was generated from human K562 erythroleukemia cells that were either unconditioned (unCond) or preconditioned with multiple heat shock exposures (preCond). After two day recovery from the preconditioning, during which the cells underwent two mitotic divisions, the cells were additionally subjected to a single heat shock to measure nascent transcription in response to heat shock in unconditioned versus preconditioned cells.

2020-03-04 | GSE127844 | GEO

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Chromatin accessibility in human K562 erythroleukemia cells profiled upon heat shock, recovery, and heat-induced transcriptional memory

Project description:Chromatin accessibility in human K562 erythroleukemia cells profiled upon heat shock, recovery, and heat-induced transcriptional memory

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Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells.

Project description:Heat-induced transcriptional memory profiled in human K562 erythroleukemia cells.

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Coral thermal tolerance: tuning gene expression to resist thermal stress

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