Regnase-1 suppresses TCF-1+ precursor exhausted T cell formation to limit CAR T cell responses against ALL [Microarray Expression]

ABSTRACT: transcriptional profiling was performed on WT and KO CAR T cells isolated 7 days after co-transfer into mice with or without tumors. Regnase-1 KO CAR T cells undergoing a tumor-dependent shift from an effector to memory-like phenotype

ORGANISM(S): Mus musculus

PROVIDER: GSE154859 | GEO | 2021/07/08

REPOSITORIES: GEO