Next Generation Sequencing of Acidosis Response in Intestinal Epithelial Cells

ABSTRACT: Purpose: The goal of this study is to define the impact of extracellular acidosis on transcriptional regulation in intestinal epithelial cells. We identify a significant induction of CREB target genes and upregulation of several genes associated with MAPK signaling. This work provides a frame work for the identification of acidosis signaling pathway in intestinal epithelial cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE154982 | GEO | 2021/05/10

REPOSITORIES: GEO