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Analysis of serum exosomal miRNAs associated with lymph node metastasis in esophageal squamous cell carcinoma

ABSTRACT: Preoperative prediction of lymph node (LN) metastasis is accepted as an important independent risk factor for treatment decision-making for esophageal squamous cell carcinoma (ESCC) patients. This study aimed to develop a non-invasive biomarker to identify LN metastasis preoperatively in ESCC patients with serum exosomal RNA-seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE155360 | GEO | 2020/07/30

REPOSITORIES: GEO

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SDR9C7 Promotes Lymph Node Metastases in Patients with Esophageal Squamous Cell Carcinoma

Project description:To identify the lymph node (LN) metastasis-associated genes in primary ESCC tumors, gene expression proﬁling assay (GEP) was performed to identify the differences in gene expression profiles between primary ESCC tumors that were with LN metastases (N+) and those without LN metastases (N-).

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Tumor metastasis to lymph node requires YAP-dependent metabolic adaptation

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