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Effect of acute systemic inflammation on the Cerebral Vasculature in mice

ABSTRACT: To capture the global gene expression patterns in the cerebral vasculature following acute systemic inflammation, we injected the mice with LPS and sacrificed them after 15 min, 30 min, and 4 hrs, followed by the isolation of the cerebral vessels. RNA was isolated from the vessel lysates, followed by library preparation and RNA sequencing.

ORGANISM(S): Mus musculus

PROVIDER: GSE155516 | GEO | 2020/12/10

REPOSITORIES: GEO

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Temporal study of the effect of acute systemic inflammation on the cerebral endothelial cells (CECs) and microglia in mice

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