Tubuloside B alleviates inflammation of murine macrophages

ABSTRACT: Purpose: Studies in mice have indicated that Tubuloside B has therapeutic potentials in various models of inflammatory diseases. We set out to analyze how Tubuloside B regulates transcription in LPS+IFN-γ-stimulated macrophages. Methods: RNA-seq was performed with two repetitions in RAW264.7 followed by treatment with Tubuloside B and LPS as well as IFN-γ. Conclusions: Tubuloside B inhibits the production of pro-inflammatory cytokines in activated macrophages.

ORGANISM(S): Mus musculus

PROVIDER: GSE155566 | GEO | 2021/07/31

REPOSITORIES: GEO