Activation of AhR by ITE in DCs induces differential gene expression over time.

ABSTRACT: To evaluate the effects of AhR activation in dendritic cells (DCs) over time, DCs isolated from human blood or murine spleens were incubated with the AhR ligand ITE for 6 hours, 18 hours, or 72 hours. Treatment with ITE was found to induce transcriptional programs associated with immunoregulatory/ immunosuppressive mchanisms.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE155712 | GEO | 2021/08/04

REPOSITORIES: GEO