Methylomic analysis of ovarian cancers identifies tumor-specific alterations readily detectable in early precursor lesions

ABSTRACT: High-grade serous ovarian carcinoma (HGSOC) typically remains undiagnosed until advanced stages when peritoneal dissemination has already occurred. Here, we sought to identify HGSOC-specific alterations in DNA methylation and assess their potential to provide sensitive and specific detection HGSOC at its earliest stages.

ORGANISM(S): Homo sapiens

PROVIDER: GSE155760 | GEO | 2020/08/06

REPOSITORIES: GEO