TNF blockade uncouples toxicity and anti-tumor efficacy induced with an agonist CD40 antibody

ABSTRACT: TNF mechanistically links cytokine release and hepatotoxicity triggered by an agonist CD40 antibody, and toxicity can be suppressed by blockade of TNF without affecting anti-tumor efficacy.

ORGANISM(S): Mus musculus

PROVIDER: GSE156160 | GEO | 2021/09/08

REPOSITORIES: GEO