Genomics

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Genome-wide analysis of the JAM-C over-expressed trophoblasts


ABSTRACT: During pregnancy, trophoblasts in the placenta are important in the success of pregnancy. We identify an adhesion molucule, JAM-C, which expresses on membrane of column cytotrophoblasts and regulates the differentiation and migration of trophoblasts. Primary cytotrophoblasts isolated from 1st trimester villi were transfected with JAM-C or control plasmids. RNA-seq analysis was sujected to identify differentially expressed genes and pathways potentially altered.

ORGANISM(S): Homo sapiens

PROVIDER: GSE156258 | GEO | 2020/10/31

REPOSITORIES: GEO

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