Methylation and chromatin abnormalities in chronic myelomonocytic leukemia.

ABSTRACT: In this study, institutional IRB approval was obtained and peripheral blood and bone marrow samples on patients with chronic myelomonocytic leukemia were collected. On the samples, we performed chromatin immuno-precipitation and next generation sequencing to assess histone modifications and epigenetic changes associated with proliferative and dysplastic phenotypes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE156377 | GEO | 2020/08/18

REPOSITORIES: GEO