Salivary gland during development and onset of xerostomia in murine model of Sjögren's syndrome-like disease

ABSTRACT: Differential gene expression in the salivary gland during development and onset of xerostomia in Sjögren’s syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse. Recently, we reported the development of the C57BL/6.NOD-Aec1Aec2 mouse that carries two genetic intervals derived from the NOD mouse capable of conferring Sjögren’s syndrome (SjS)-like disease in SjS-non-susceptible C57BL/6 mice. In an attempt to define the molecular bases underlying onset of stomatitis sicca (xerostomia) in this C57BL/6.NOD-Aec1Aec2 mouse model, we have carried out a study utilizing microarray technology.

ORGANISM(S): Mus musculus

PROVIDER: GSE15640 | GEO | 2009/04/11

SECONDARY ACCESSION(S): PRJNA115643

REPOSITORIES: GEO