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ATAC-seq identifies chromatin landscapes linked to the regulation of oxidative stress in the human fungal pathogen Candida albicans

ABSTRACT: ATAC-seq analysis of Candida albicans SC5314 treated or not treated with hydrogen peroxide to assess the accessible chromatin landscape upon oxidative stress in comparison to normal growth in YPD at 30 °C.

ORGANISM(S): Candida albicans

PROVIDER: GSE156582 | GEO | 2020/09/27

REPOSITORIES: GEO

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Transcriptomes of C. albicans aox2 deletion mutant or wild-type C. albicans SC5314 treated with pyocyanin

Project description:We compared the early gene expression profiles (30 min) of log-phase wild type C. albicans SC5314 growing in YPD at 30 °C to an aox2 deletion mutant or to wild-type SC5314 in response to 80 micromolar pyocyanin or 0.5 mM SHAM

2019-07-26 | GSE117717 | GEO

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Project description:Comparison of Candida albicans SC5314 treated with fludioxonil for 30 min and untreated controls under hyphae-inducing conditions

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Whole genome sequencing of ketoconazole adaptors in Candida albicans

Project description:Candida albicans lab strain SC5314 was spread on YPD plates supplemented with ketoconazole (0.125-16μg/ml); Randomly 3 adaptors from each plate were sequenced.

2023-06-15 | E-MTAB-12803 | biostudies-arrayexpress

Whole genome sequencing of fluconazole tolerant adaptors derived from exposure to echinocandins in Candida albicans

Project description:Candida albicans lab strain SC5314 was spread on YPD plates supplemented with echinocandins (caspofungin, anidulafungin, micafungin, rezafungin). The adaptors were tested for tolrance to fluconazole. Randomly 43 tolerant adaptors, as well as the parent SC5314, were sequenced.

2023-07-11 | E-MTAB-12449 | biostudies-arrayexpress

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Whole genome sequencing of Chr3x3 derived brefeldin A adpators in Candida albicans

Project description:In Candida albicans, SC5314 is the wild type strain. FY1398 is Chr3 trisomy strain derived from SC5314. In this study, approximately 1 million cells of FY1398 were spread on YPD plate supplemented with 128 ug/ml brefeldin A. Randomly 18 adpators (LH40-LH57) were chosen. These adaptors were sequenced.

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Comparison of Candida albicans lab strain SC5314 grown at different temperatures

Project description:Candida albicans lab strain SC5314 was grown in YPD broth at 30C and 37C from OD600=0.1 till 1.0. Cells were harvested and flash frozen in liquid nitrogen. Then the transcriptome was compared.

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Expt 6---Comprative transcriptomics of euploid and aneuploid Candida albicans strains

Project description:Candida albicans lab strain SC5314, which is a euploid diploid, was used to generate aneuploid fluconazole adaptors. Transcriptomes of aneuploids were compared to the euploid parent by growing cells in rich YPD broth.

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Whole genome sequencing of caspofungin adaptors in Candida albicans

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Whole genome sequencing of papillary colonies on YPD plate supplemented with tebuconazole in Candida albicans

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