Identification of genes regulated by Fer2 in the fly brain using an overexpression approach
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ABSTRACT: The transcription factor Fer2 plays a neuroprotective role in the dopaminergic neurons of the fly brain, but the underlying molecular mechanisms are not understood. By performing RNA-seq on fly heads after Fer2 inducible overexpression, we identified hundreds of genes differentially regulated in response to Fer2 overexpression. Combining this dataset with Fer2 ChIP-seq on the fly head, we obtained a list of 26 direct target genes, bound and regulated by Fer2.
ORGANISM(S): Drosophila melanogaster
PROVIDER: GSE156890 | GEO | 2020/08/27
REPOSITORIES: GEO
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