Single-cell RNA sequencing of niche cells from WT, BMT and aGVHD mice

ABSTRACT: We performed scRNA-seq of non-hematopoietic cells from non-treated control (WT), BMT and aGVHD mice. Unsupervised clustering, sub-clustering based on gene expression and trajectory analysis converged on the conclusion that aGVHD likely disrupts MSC differentiation potential, especially osteogenesis.

ORGANISM(S): Mus musculus

PROVIDER: GSE157389 | GEO | 2021/08/09

REPOSITORIES: GEO