Genomics

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ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer [ERG ChIP]

ABSTRACT: We report the effects of ERG on prostate tumorigenesis, ERG-mediated oncogene addiction, and downstream AR signaling pathways. We determined that ERG facilitates AR-signaling and mediates transformation of prostate cells by maintaining coregulator complex formation at AR-bound sites across the genome.

ORGANISM(S): Mus musculus

PROVIDER: GSE157406 | GEO | 2020/09/04

REPOSITORIES: GEO

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