Pretreatment of aged mice with retinoic acid restores alveolar regeneration via upregulation of reciprocal PDGFRA signaling

ABSTRACT: Reciprocal PDGFA signaling activates regenerative fibroblasts that support alveolar epithelial cell differentiation and repair, providing a potential therapeutic strategy to influence the pathogenesis of IPF.

ORGANISM(S): Mus musculus Homo sapiens

PROVIDER: GSE157440 | GEO | 2021/01/05

REPOSITORIES: GEO