Genomics

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Identification of genes regulated by Fer2 in PAM neurons using an overexpression approach


ABSTRACT: The transcription factor Fer2 plays a neuroprotective role in the dopaminergic neurons of the fly brain, but the underlying molecular mechanisms are not understood. By performing RNA-seq on isolated dopaminergic PAM neurons after Fer2 constitutive overexpression, we identified over one hundred genes differentially regulated in response to PAM-specific Fer2 overexpression.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE157589 | GEO | 2020/09/08

REPOSITORIES: GEO

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