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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo [scRNA-seq]

ABSTRACT: scRNA-sequencing of human xenotransplanted microglia isogenic for TREM2 after exposure to amyloid pathology

ORGANISM(S): Homo sapiens

PROVIDER: GSE158234 | GEO | 2020/09/19

REPOSITORIES: GEO

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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer’s pathology in vivo [RNA-seq]

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Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's Disease model

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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo

Project description:This SuperSeries is composed of the SubSeries listed below.

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Transcriptomic and functional deficits in human TREM2-/- microglia impair response to Alzheimer's pathology in vivo

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