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Differentially expressed lncRNA in biological premature ovarian insufficient(bPOI)

ABSTRACT: We have completed the lncRNA expression profiling of human granulosa cells to reveals the differentially expressed lncRNAs involved in POI.

ORGANISM(S): Homo sapiens

PROVIDER: GSE158526 | GEO | 2021/02/20

REPOSITORIES: GEO

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Differentially expressed lncRNA in biological premature ovarian insufficiency (bPOI)

Project description:Our study is designed to demonstrate altered profiles of lncRNAs in the granulosa cells from patients with bPOI. Functional studies will be further confirmed. This study will provide new viewpoint for understanding the roles of non-coding RNA for GCs function, as well as potential etiologic mechanism for POI.

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Project description:This study is to identify urinary exosome microRNAs (miRNAs) that are unique to premature ovarian insufficiency (POI) with and without Turner syndrome and to use them as diagnostic markers for POI patients. We examined the miRNAexpression profile in urine exosomes from POI patients with and without Turner syndrome.

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