Long-Term Soy Protein Isolate Intake Reduces Liver Steatosis through Changes in Global Gene Expression in Obese Zucker Rats

ABSTRACT: To understand how soy protein isolate (SPI) reduced liver steatosis in male obese Zucker rats, we conducted global gene expression (RNAseq) analysis on liver samples of male rats fed either the SPI or a control casein (CAS)-based diet (n=8 per group) for 16 wks. Bioinformatics was conducted using Ingenuity Pathway Analysis (IPA) software (Qiagen, CA) with P < 0.05 and 1.3 fold differential expression cutoff values.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE158553 | GEO | 2020/11/11

REPOSITORIES: GEO