Protein prenylation drives discrete signaling programs for the differentiation and maintenance of effector Treg cells [Microarray Dataset 3]

ABSTRACT: An interplay between immune signals, isoprenoids-mediated protein prenylation, and intracellular signaling for the differentiation and maintenance of eTreg cells. We used microarrays to compare the global transcription profiles of in vitro activated CD4+YFP+CD44loCD62Lhi cTreg cells sorted from Foxp3YFP-Cre mice and activated by 10 ug/ml anti-CD3/28 antibodies plus 200 U/ml IL-2 for different time points in the presence of prenylation inhibitors

ORGANISM(S): Mus musculus

PROVIDER: GSE158862 | GEO | 2021/01/20

REPOSITORIES: GEO