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Sox9 deficiency effect on mouse mammary gland

ABSTRACT: RNA from MMTV-Cre;Sox9flox/flox mouse mammary glands were compared to RNA from MMTV-Cre;Sox9+/flox glands. Results indicate that Sox9 regulates several genes that impact ductal morphogenesis in the mammary gland.

ORGANISM(S): Mus musculus

PROVIDER: GSE15917 | GEO | 2009/05/02

SECONDARY ACCESSION(S): PRJNA116919

REPOSITORIES: GEO

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Sox9 deficiency effect on mouse mammary gland

Project description:RNA from MMTV-Cre;Sox9flox/flox mouse mammary glands were compared to RNA from MMTV-Cre;Sox9+/flox glands. Results indicate that Sox9 regulates several genes that impact ductal morphogenesis in the mammary gland. The portion of the fourth mammary gland that is proximal to the intra-mammary gland lymph nodes was dissected from four 5-week-old MMTV-Cre;Sox9flox/flox females and four MMTV-Cre;Sox9+/flox females of the same age. Total RNA from each gland was extracted and hybridized to separate Affymetrix Gene 1.0 ST chips.

2010-04-09 | E-GEOD-15917 | biostudies-arrayexpress

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Effects of iFGFR1 activation in the mammary gland

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