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Genetic alterations of SUGP1 mimic mutant-SF3B1 splice pattern in lung adenocarcinoma and other cancers

ABSTRACT: RNA-sequencing data from HEK293T and HAP1 cell models: Hek293T (SF3B1-K700E, SF3B1-WT, SUGP1-KD and siContol), HAP1 CRISPR-isogenic cell lines WT and SUGP1-P636L

ORGANISM(S): Homo sapiens

PROVIDER: GSE159304 | GEO | 2020/10/10

REPOSITORIES: GEO

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Functional and conformational impact of cancer-associated SF3B1 mutations depends on the position and the charge of amino acid substitution

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