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Establishment of hTERT immortalized mouse cardiosphere derived cell line.

ABSTRACT: The analysis showed differences of transcriptomes between 5-azacytidine induced CDCs and control CDCs. We identified 10uM 5-azacytidine treatment for 3 days, following with normal culture for 4 weeks,could induce hTERT immortlized CDCs cardiac differentiation. Differential gene expression cluster analysis indicated big difference after 5-aza treatment, which include cardiomyocyte specific genes,such as tnnt2,desmin,mef2a,etc.

ORGANISM(S): Mus musculus

PROVIDER: GSE159640 | GEO | 2020/10/20

REPOSITORIES: GEO

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Establishment of hTERT immortalized mouse cardiosphere derived cell line

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