Loss of claudin-3 impairs hepatic metabolism, biliary-barrier function and cell proliferation in the murine liver

ABSTRACT: We determined the functional role of the tight junction protein Claudin-3 for overall gene expression in the liver. In the bulk RNAseq, we compare global gene expression in the livers of C57BL/6 wildtype mice and in CLDN3-/- mice. We sequenced both normal liver tissue and regenerating liver tissue.

ORGANISM(S): Mus musculus

PROVIDER: GSE159914 | GEO | 2021/07/01

REPOSITORIES: GEO