Using DMS-MaPseq to dissect structural differences of ribosomal RNA in different pre-40S intermediates

ABSTRACT: Ribosomes are among the largest folded RNAs, whose function depends on their structure. Nonetheless, in vitro studies indicate a propensity of rRNAs to misfold. We use a combination of DMS-MaPseq, structural analyses, biochemical experiments, and yeast genetics to dissect the final RNA folding steps of the small ribosomal subunit head.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE160161 | GEO | 2021/06/04

REPOSITORIES: GEO