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RNA-seq for polyphenols treated Pseudomonas syringae

ABSTRACT: Bacteria use a variety of mechanisms, such as two‐component regulatory systems (TCSs), to rapidly sense and respond to distinct conditions and signals in their host organisms. For example, a type III secretion system (T3SS) is the key determinant of the virulence of the model plant pathogen Pseudomonas syringae and contains the TCS RhpRS as a key regulator. However, the signal sensed by RhpRS remains unknown. We found that RhpRS directly senses plant-generated polyphenols and responds by switching off P. syringae T3SS via crosstalk with alternative histidine kinases. Through a chemical screen, we identified three natural polyphenols (tannic acid, 1,2,3,4,6-pentagalloylglucose and epigallocatechin gallate) that induced the expression of the rhpRS operon in a RhpS-dependent manner.

ORGANISM(S): root metagenome Pseudomonas savastanoi pv. phaseolicola 1448A

PROVIDER: GSE160492 | GEO | 2021/09/20

REPOSITORIES: GEO

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RNA-seq for polyphenols treated Pseudomonas syringae

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