Project description:Label-free based phospho-proteomic was used to analysis protein phosphorylation profile of L02 hepatocytes with or without 0.5 mM PA stimulate in condition of DMSO or 10 μM sorafenib for 18h
Project description:We established a BCG-infected THP-1 cell model in vitro, obtained the total RNA of cell culture supernatant exosomes and total RNA of the infected group and the uninfected group, and performed miRNA sequencing analysis to find exosomes related to tuberculosis infection The body-derived miRNA is verified by cell lines and primary cells, and the diagnostic value of small sample clinical samples and preliminary functional research and exploration are explored for candidate molecules.