Vitamin D Receptor binding and chromatin accessibility in mouse duodenal crypt and villus and colon epithelium
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ABSTRACT: VDR is critical for Ca++ homeostasis. While its role in this process within the intestine has primarily been focused to the duodenal epithelium, we have uncovered a compensatory role for VDR in the colon in mediating Ca++ uptake. Here, we compare VDR genomic binding properties in the colon and duodenum using ChIP-seq. We also examine the chromatin accessibility between these intestinal regions.
ORGANISM(S): Mus musculus
PROVIDER: GSE161038 | GEO | 2023/11/06
REPOSITORIES: GEO
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