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Skeletal Stem Cell Diversity in Mouse Long Bones

ABSTRACT: We have used SmartSeq2 to sequence single phenotypic skeletal stem cell (SSCs) populations purified via FACS from adult mouse long bones. Two putative SSC populations were isolated based on their previously reported surface marker profiles. An osteochondrogenic SSC (ocSSC, CD45-CD31-Tie2-Ter119-CD51+6C3-Thy1-CD105-) and a perivascular SSC (pvSSC, CD45-CD31-Pdgfra+Sca1+CD24+) were investigated.

ORGANISM(S): Mus musculus

PROVIDER: GSE161477 | GEO | 2021/06/11

REPOSITORIES: GEO

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