Transcriptomic analysis of THAP1 mediated oligodendrocyte development

ABSTRACT: We demonstrated previously that THAP1 plays a cell-autonomous role in regulating myelination during early postnatal CNS development (Yellajoshyula et al., Dev Cell, 42, 52-67, 2017). To begin to examine the mechanisms responsible for this role, we performed RNAseq at multiple time points on cultured control (Thap1+/+) and Thap1 null (derived from Thap1flx/-; Olig2-Cre+) OPC under differentiating conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE161556 | GEO | 2021/04/24

REPOSITORIES: GEO