Transcriptional profiing of cultured adherent and non-adherent monocytes

ABSTRACT: To determine the effect of adherence on the metabolic and functional response of human monocytes. Monocytes were stimulated with lipopolysaccharide (LPS) under non-adherent and adherent conditions. To determine the role of glycolysis in LPS-induced immune responses, this pathway was inhibited by glucose deprivation or the glucose analog 2-deoxy-D-glucose (2DG).

ORGANISM(S): Homo sapiens

PROVIDER: GSE161839 | GEO | 2020/12/08

REPOSITORIES: GEO