A Cell Atlas of Microbe-Responsive Processes in the Zebrafish Intestine

ABSTRACT: To understand intestinal cell-specific responses to host commensal bacteria, we isolated single cells from intestines and associated tissue of zebrafish larvae raised in the presence or absence of a microbiome. We profiled cells with single-cell RNA-seq. Our analysis revealed extensive heterogeneity among cell populations of the fish intestine and associated tissue, and describe distinct microbial responses in each cell type.

ORGANISM(S): Danio rerio

PROVIDER: GSE161855 | GEO | 2020/11/20

REPOSITORIES: GEO