Single-cell mRNA profiling reveals changes in solute carrier expression and a metabolic switch during zebrafish pronephros development

ABSTRACT: Developing organisms need to adapt to environmental variations as well as to rapid changes in substrate availability and energy demands imposed by fast-growing tissues and organs. Little is known about the adjustments that kidneys undergo in response to these challenges. We performed single-cell RNA sequencing of zebrafish pronephric duct cells to understand how the developing kidney responds to changes in filtered substrates and intrinsic energy requirements.

ORGANISM(S): Danio rerio

PROVIDER: GSE162031 | GEO | 2021/03/18

REPOSITORIES: GEO