Genome-wide gene expression analysis for CRISPRi targeting a human SFTPB locus bound by NKX2-1

ABSTRACT: RNA-seq was performed to identify genes affected by CRISPRi (dCas9-KRAB) with sgRNA (sgSFTPB#2) targeting the first intronic region of human SFTPB bound by NKX2-1 in an unbiased genome-wide fashion using A549 lung carcinoma cells that constitutively express dCas9-KRAB and NKX2-1.

ORGANISM(S): Homo sapiens

PROVIDER: GSE162186 | GEO | 2021/03/25

REPOSITORIES: GEO