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Differentially expressed mRNAs with statistical significance in cisplatin treated wild-type PTECs infected with Ad-FXRα2 or Ad-VP16

ABSTRACT: We report the application of RNA-sequence in Primary PTECs, by obtaining the sequence from cisplatin treated wild-type PTECs infected with Ad-FXRα2 or Ad-VP16

ORGANISM(S): Mus musculus

PROVIDER: GSE162279 | GEO | 2020/11/28

REPOSITORIES: GEO

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Differentially expressed mRNAs with statistical significance in cisplatin treated wild-type PTECs infected with Ad-FXRα2 or Ad-VP16

Project description:Differentially expressed mRNAs with statistical significance in cisplatin treated wild-type PTECs infected with Ad-FXRα2 or Ad-VP16

| PRJNA681238 | ENA

Vibrio parahaemolyticus strain:VP16 | isolate:VP16

Project description:Vibrio parahaemolyticus strain:VP16 | isolate:VP16 Genome sequencing

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Genome-wide analysis of gene expression profile of Xenograft Tumors (HT29 cells) grown in Nu/Nu Athymic Female Mice infected with Control (Ad-VP16) or LXRa (VP16hLXRa) Adenovirus

Project description:Changes in gene expression profile of Xenograft Tumors (HT29 cells) grown in Nu/Nu Athymic Female Mice infected with Control (Ad-VP16) or LXRa (VP16hLXRa) Adenovirus. The hypothesis tested in the present study was that LXRa overexpression influence cancer growth modulating lipid metabolism in cancer cells. Results provide the information that LXRa induces genes encoding proteins able to regulate cholesterol efflux thus reducing tumor growth. Total RNA obtained from Xenograft Tumors (HT29 cells) grown in Nu/Nu Athymic Female Mice infected with LXRa (VP16hLXRa) Adenovirus was compared to total RNA extracted from Xenografted Tumors (HT29 cells) grown in Nu/Nu Athymic Female Mice infected with Control (Ad-VP16) Adenovirus.

2013-02-05 | E-GEOD-44068 | biostudies-arrayexpress

Genome-wide analysis of gene expression profile of Xenograft Tumors (HT29 cells) grown in Nu/Nu Athymic Female Mice infected with Control (Ad-VP16) or LXRa (VP16hLXRa) Adenovirus

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SRF-VP16 overexpression in ES cells

Project description:Empty vector, SRF-dM-VP16 (control construct lacking the SRF DNA binding domain), or SRF-VP16 were expressed in wild-type ES cells (E14wt), SRF heterozygotes (E99-/+) or two SRF ko cell lines (E81-/-,E100-/-). RNA was harvested 72h after transfection. Each condition was performed in duplicate, except E100-/- vector transfected. Keywords: ordered

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Sef1-VP16 dependent gene expression in Lachancea kluyveri

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Gene expression analysis of untreated and NT-shRNA transduced kidney proximal tubular epithelial cells (PTECs) at day 6 and day 16 after transduction, as well as SETD2-shRNA transduced PTECs at day 25 after transduction.

Project description:Primary kidney PTECs gradually became senescesince day 16, but SETD2 depletion prevented PTECs from senescence and maintained their proliferation beyond their limited dividing capacity. Transcriptional profiling of human PTECs, with comparing of non-senescent PTECs (PTECs-day 6), senescent PTECs (PTECs-day16), and SETD2 depleted PTECs at day 25 (SETD2 KD-PTECs-day 25). Three PTECs of different origins were transduced with shRNA constructs against SETD2 (sh1 or sh2), or with a non-targeting sequence. Untreated and NT-shRNA transduced samples were harvest at day 6 and day 16 respectively, SETD2-KD shRNA transduced PTECs were harvest at day 25.

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Large scale investigation of the phage Vp16 PDF activity

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2017-09-25 | PXD006008 | Pride

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2006-01-12 | GSE3965 | GEO

Gene expression of HEK 293 cells transfected with Vector (PCMV), Aire, or MBD-VP16

Project description:HEK 293 cells were transiently transfected with plasmids expressing Vector only(PCMV), Aire, or MBD-VP16 with the goal of comparing the global gene expression profiles in the Aire and MBD-VP16 groups We used microarrays to detail the global gene expression profile.

2013-11-21 | GSE52546 | GEO

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