Transcriptomics

Dataset Information

0

Vascular integrity is essential for maintaining tissue homeostasis II


ABSTRACT: Purpose: analyze the transcriptomic difference of endothelial cells and pericytes in PBS, LPS or LPS + Riociguat treated lungs Methods: Gucy1a1-EGFP mice were given PBS or LPS treatment via trachea instillation. Vehicle or Riociguat oral administation was performed at every 9 hours. 24h later, lungs were dissociated and endothelial cells and pericytes were isolated by flow cytometry, then directly processed to RNA extraction and library construction Results: Riociguat can restore LPS-induced lung injury by inhibiting pericytes activation and maintain vascular homostatsis

ORGANISM(S): Mus musculus

PROVIDER: GSE162351 | GEO | 2021/06/01

REPOSITORIES: GEO

Similar Datasets

2021-06-01 | GSE162328 | GEO
2021-06-01 | GSE162354 | GEO
2022-07-13 | GSE207868 | GEO
2013-02-01 | GSE34814 | GEO
2013-02-01 | GSE34812 | GEO
2013-02-01 | E-GEOD-34814 | biostudies-arrayexpress
2020-10-20 | GSE159236 | GEO
2013-02-01 | E-GEOD-34812 | biostudies-arrayexpress
2011-01-13 | E-GEOD-26567 | biostudies-arrayexpress
2012-08-03 | E-GEOD-38398 | biostudies-arrayexpress